Rental Property That Is Not In The Best Of Areas?

I have two psychiatrists that are father & the daughter just got out of school. They want to rent my duplex that is not in the best of areas and want to have their clients there and make this their office. They want a two year contract for $850 and not $875 that I have it listed for. Why would a psychiatrist want in an area that is not really where I would even live and can you even run a business out of a duplex like that when it is rental property?